منابع مشابه
Correlation between expression of matrix metalloproteinase-2 (MMP-2), and matrix metalloproteinase-9 (MMP-9) and angiogenesis in colorectal adenocarcinoma.
Matrix metalloproteinases-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9), which degrade extracellular matrix, are believed to play a crucial role in tumor invasion and metastasis. Angiogenesis is also perceived as an important step in tumor growth and metastasis. To investigate the expression of MMPs and the correlation between the expression of MMPs and angiogenesis in colorectal adenocarcin...
متن کاملThe Effect of Adiponectin on Matrix Metalloproteinase-9 (MMP-9) in Vascular Smooth Muscle Cells
Background & Aims: Atherosclerosis is a major cause of morbidity and mortality. Adiponectin reducesthe risk of heart disease, and matrix metalloproteinase-9 (MMP-9) is involved in the formation and development of atherosclerotic plaque. The aim of this study was the investigation of the effect of adiponectin on MMP-9 gene expression. It seems this hormone can reduce the risk of atherosclerosis ...
متن کاملRegulation of matrix metalloproteinase (MMP) gene expression by protein kinases.
Matrix metalloproteinases (MMPs) are a family of structurally and functionally related zinc-containing endopeptidases that are capable of degrading almost all of the components of the extracellular matrix (ECM). Under physiological and pathological conditions, the MMPs play a significant role in the efficient tissue turnover and remodeling. Specific MMPs are responsible for the matrix degradati...
متن کاملRegulation of matrix metalloproteinase-2 (MMP-2) activity by phosphorylation.
The regulation of matrix metalloproteinases (MMP) has been studied extensively due to the fundamental roles these zinc-endopeptidases play in diverse physiological and pathological processes. However, phosphorylation has not previously been considered as a potential modulator of MMP activity. The ubiquitously expressed MMP-2 contains 29 potential phosphorylation sites. Mass spectrometry reveals...
متن کاملSalivary matrix metalloproteinase (MMP)-8 as a biomarker for periodontitis
BACKGROUND Salivary matrix metalloproteinase (MMP)-8 is currently considered to be one of the most promising biomarkers for early diagnosis of periodontitis, however, several recent studies showed conflicting results. OBJECTIVE To determine the salivary matrix metalloproteinase (MMP)-8 levels between periodontitis patients and healthy individuals, and to assess its diagnostic value in periodo...
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ژورنال
عنوان ژورنال: Biomedical and Pharmacology Journal
سال: 2016
ISSN: 0974-6242
DOI: 10.13005/bpj/1025